Molecular Heterogeneity of the PML Gene Rearrangement in Acute Promyelocytic Leukemia: Prevalence and Clinical Significance

We determined the breakpoints of the RAR‐α and PML genes in acute promyelocytic leukemia (APL) cells from 40 patients using Southern blot analysis. We also analyzed the relationship between the location of breakpoints, the clinical features of APL and the response to all‐trans retinoic acid (ATRA)....

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Detalles Bibliográficos
Autores principales: Fukutani, Hisashi, Naoe, Tomoki, Yoshida, Hitoshi, Yamamori, Shunji, Ohno, Ryuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919144/
https://www.ncbi.nlm.nih.gov/pubmed/8387477
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02865.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919144/
https://www.ncbi.nlm.nih.gov/pubmed/8387477
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02865.x

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