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Cell‐density‐dependent Expression of Cyp1a2 Gene in Monolayer‐cultured Adult Mouse Hepatocytes

Expression of Cyp1a1 and Cyp1a2 genes was investigated in adult C57BL/6NCrj mouse hepatocytes for up to 5 days after transfer to monolayer culture. CYP1A1 mRNA was substantially induced by treatment with 3‐methylcholanthrene during the observation period, independently of the seeded cell density. Ho...

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Detalles Bibliográficos
Autores principales: Nemoto, Nobuo, Sakurai, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919153/
https://www.ncbi.nlm.nih.gov/pubmed/8486527
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02866.x