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Structure of 85 kDa Subunit of Human Phosphatidylinositol 3‐Kinase Analyzed by Using Monoclonal Antibodies

An 85 kDa subunit (p85α) of phosphatidylinositol 3‐kinase (PI‐3K) has one SH3 and two SH2 regions [SH2(N) and SH2(C)], which direct protein‐protein interaction. We have established eighteen hybridomas producing monoclonal antibodies against p85α to study the structure‐function relationship of this p...

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Detalles Bibliográficos
Autores principales: Tanaka, Shinya, Matsuda, Michiyuki, Nagata, Satoshi, Kurata, Takeshi, Nagashima, Kazuo, Shizawa, Yasuhiko, Fukui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919156/
https://www.ncbi.nlm.nih.gov/pubmed/7683636
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02868.x