Cargando…

Structure of 85 kDa Subunit of Human Phosphatidylinositol 3‐Kinase Analyzed by Using Monoclonal Antibodies

An 85 kDa subunit (p85α) of phosphatidylinositol 3‐kinase (PI‐3K) has one SH3 and two SH2 regions [SH2(N) and SH2(C)], which direct protein‐protein interaction. We have established eighteen hybridomas producing monoclonal antibodies against p85α to study the structure‐function relationship of this p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Shinya, Matsuda, Michiyuki, Nagata, Satoshi, Kurata, Takeshi, Nagashima, Kazuo, Shizawa, Yasuhiko, Fukui, Yasuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1993
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919156/ https://www.ncbi.nlm.nih.gov/pubmed/7683636 http://dx.doi.org/10.1111/j.1349-7006.1993.tb02868.x

Ejemplares similares

Cellular and Tissue Distribution of MRK20 Murine Monoclonal Antibody‐defined 85‐kDa Protein in Adriamycin‐resistant Cancer Cell Lines
por: Sugawara, Isamu, et al.
Publicado: (1988)

A Novel Multidrug Resistance in Cultured Leukemia and Lymphoma Cells Detected by a Monoclonal Antibody to 85‐kDa Protein, MRK20
por: Ohtsu, Tomoko, et al.
Publicado: (1989)

Essential functions of the 32 kDa subunit of yeast replication protein A
por: Dickson, Anne M., et al.
Publicado: (2009)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

Crystal structure of the 25 kDa subunit of human cleavage factor I(m)
por: Coseno, Molly, et al.
Publicado: (2008)

Increased constitutive activity of mitogen-activated protein kinase and renaturable 85 kDa kinase in human-colorectal cancer.
por: Ostrowski, J., et al.
Publicado: (1998)

Data on physicochemical properties of LPEI 25 kDa, PEI“Max” 40 kDa and PEIpro™
por: Delafosse, Laurence, et al.
Publicado: (2016)

Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).
por: Hipfner, D. R., et al.
Publicado: (1998)

Expression Behavior of 85‐kDa Membrane Protein in Adriamycin‐resistant Tumor Cells and the Inhibition of Human Tumor Growth in Athymic Mice by MRK‐20 Monoclonal Antibody against the Protein
por: Ishii, Shigetaka, et al.
Publicado: (1993)

In Vitro Inhibition of Angiogenesis by Antibodies Directed against the 37kDa/67kDa Laminin Receptor
por: Khusal, Raksha, et al.
Publicado: (2013)

Expression of 85‐kDa Protein of Adriamycin‐resistant Tumor Cells during Hematopoietic Differentiation of THP‐1 and HEL Cells
por: Ishii, Shigetaka, et al.
Publicado: (1992)

Phosphatidylinositol Monophosphates Regulate the Membrane Localization of HSPA1A, a Stress-Inducible 70-kDa Heat Shock Protein
por: Smulders, Larissa, et al.
Publicado: (2022)

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura
por: Xiao, Chengfeng, et al.
Publicado: (2004)

Identification of Binding Sites for Neutralizing Monoclonal Antibodies on the 14-kDa Fusion Protein of Orthopox Viruses
por: Meyer, Hermann, et al.
Publicado: (1994)

The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ(42) internalization
por: Da Costa Dias, Bianca, et al.
Publicado: (2014)

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity
por: Naidoo, Kerrilyn, et al.
Publicado: (2015)

Enhanced gene transfection efficiency by low-dose 25 kDa polyethylenimine by the assistance of 1.8 kDa polyethylenimine
por: Zhang, Hui, et al.
Publicado: (2018)

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis
por: Stephan, Holger, et al.
Publicado: (2009)

Cross Protectivity Analysis of 49.8 kDa Pili Subunits of S. flexneri against Vibrio cholerae Infection
por: Yuni Nur Hidayati, Dwi, et al.
Publicado: (2022)

Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85α and p85β
por: Ito, Yoshihiro, et al.
Publicado: (2017)

The 18 kDa Translocator Protein, Microglia and Neuroinflammation
por: Liu, Guo‐Jun, et al.
Publicado: (2014)

Enhanced Cell Killing by Overexpression of Dominant‐negative Phosphatidylinositol 3‐Kinase Subunit, Δp85, Following Genotoxic Stresses
por: Tachiiri, Seiji, et al.
Publicado: (2000)

Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats
por: Hampe, Christiane S, et al.
Publicado: (2013)

A test of the model that RNA polymerase III transcription is regulated by selective induction of the 110 kDa subunit of TFIIIC
por: Innes, Fiona, et al.
Publicado: (2006)

A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor
por: Addepalli, Balasubrahmanyam, et al.
Publicado: (2007)

Molecular Cloning and Expression an 8-kDa Subunit of Antigen B from G1 strain of Echinococcus granulosus
por: AZIZI, Hakim, et al.
Publicado: (2015)

Monodisperse 130 kDa and 260 kDa Recombinant Human Hemoglobin Polymers as Scaffolds for Protein Engineering of Hemoglobin-Based Oxygen Carriers
por: Marquardt, David A., et al.
Publicado: (2012)

MALDI-TOF High Mass Calibration up to 200 kDa Using Human Recombinant 16 kDa Protein Histidine Phosphatase Aggregates
por: Ludwig, Katrin, et al.
Publicado: (2011)

Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells
por: Folgiero, V, et al.
Publicado: (2012)

Development and Characterization of Monoclonal Antibodies to the 32 kDa Viral Attachment Protein of Lymphocystis Disease Virus and Their Neutralizing Ability in Vitro
por: Zhong, Ying, et al.
Publicado: (2018)

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin
por: Wei, Hung-Mu, et al.
Publicado: (2016)

Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei
por: Rehic, Edisa, et al.
Publicado: (2019)

The Role of Heat Shock Protein 70 kDa in Asthma
por: Shevchenko, Marina, et al.
Publicado: (2021)

Identification and Characterization of a Trypanosoma congolense 46 kDa Protein as a Candidate Serodiagnostic Antigen
por: ZHOU, Mo, et al.
Publicado: (2014)

Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs
por: Kubo, Tomohiro, et al.
Publicado: (2006)

Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex
por: Kluge, Christoph, et al.
Publicado: (2004)

The 25 kDa Subunit of Cleavage Factor Im Is a RNA-Binding Protein That Interacts with the Poly(A) Polymerase in Entamoeba histolytica
por: Pezet-Valdez, Marisol, et al.
Publicado: (2013)

ND3, ND1 and 39 kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I
por: Babot, Marion, et al.
Publicado: (2014)

High Resolution Imaging Study of Interactions between the 37 kDa/67 kDa Laminin Receptor and APP, Beta-Secretase and Gamma-Secretase in Alzheimer's Disease
por: Jovanovic, Katarina, et al.
Publicado: (2014)

Identification of the Interactors of Human Nibrin (NBN) and of Its 26 kDa and 70 kDa Fragments Arising from the NBN 657del5 Founder Mutation
por: Cilli, Domenica, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fr8j6p3lsuln4dqecr4vmnrvav