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Enhancement of Reversing Effect of Cyclosporin A on Vincristine Resistance by Anti‐P‐glycoprotein Monoclonal Antibody MRK‐16
The synergistic effect of MRK‐16, a monoclonal antibody against P‐glycoprotein, and cyclosporin A (CsA) on the modulation of vincristine resistance was studied by isobologram analysis in three different, highly multidrug‐rcsistant tumor cells. In all cell lines, the synergistic effect was demonstrat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919166/ https://www.ncbi.nlm.nih.gov/pubmed/8100562 http://dx.doi.org/10.1111/j.1349-7006.1993.tb00164.x |