ED‐110, a Novel Indolocarbazole, Prevents the Growth of Experimental Tumors in Mice

A new indolocarbazole compound, ED‐110, which was obtained by glucosylating a microbial product (BE‐13793C) and is a potent topoisomerase I inhibitor, showed characteristic inhibitory effects on the growth of 12 human tumor cell lines tested. The IC(50) values of ED‐110 against 9 of the 12 lines ran...

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Detalles Bibliográficos
Autores principales: Arakawa, Hiroharu, Iguchi, Tomoko, Yoshinari, Tomoko, Kojiri, Katsuhisa, Suda, Hiroyuki, Okura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919172/
https://www.ncbi.nlm.nih.gov/pubmed/8320174
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00178.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919172/
https://www.ncbi.nlm.nih.gov/pubmed/8320174
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00178.x

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