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ED‐110, a Novel Indolocarbazole, Prevents the Growth of Experimental Tumors in Mice
A new indolocarbazole compound, ED‐110, which was obtained by glucosylating a microbial product (BE‐13793C) and is a potent topoisomerase I inhibitor, showed characteristic inhibitory effects on the growth of 12 human tumor cell lines tested. The IC(50) values of ED‐110 against 9 of the 12 lines ran...
Autores principales: | Arakawa, Hiroharu, Iguchi, Tomoko, Yoshinari, Tomoko, Kojiri, Katsuhisa, Suda, Hiroyuki, Okura, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919172/ https://www.ncbi.nlm.nih.gov/pubmed/8320174 http://dx.doi.org/10.1111/j.1349-7006.1993.tb00178.x |
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