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Antimetastatic Activity of Polymeric RGDT Peptides Conjugated with Poly(ethylene glycol)

Polymeric peptides containing defined repetitive or cyclic structures of RGDT sequence, (RGDT)(n) (n = 1 to 11) and cyclo(RGDT)(n) (n=2 to 4), at a dose of 500 μg exhibited an inhibitory effect on experimental lung metastasis upon co‐injection with tumor cells and the magnitude of the effect increas...

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Detalles Bibliográficos
Autores principales: Saiki, Ikuo, Yoneda, Junya, Igarashi, Yu, Aoki, Miho, Kusunose, Naoto, Ono, Kei‐ichi, Azuma, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919174/
https://www.ncbi.nlm.nih.gov/pubmed/8320173
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00176.x