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Genetic Alterations in Thyroid Tumor Progression: Association with p53 Gene Mutations

To identify the genetic events that must be involved in thyroid tumor progression, we initially investigated p53 gene alterations in 10 papillary adenocarcinomas, 4 follicular adenocarcinomas, and 8 undifferentiated carcinomas. Base substitutional mutations in exons 5 to 8 and loss of heterozygosity...

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Detalles Bibliográficos
Autores principales: Ito, Takashi, Seyama, Toshio, Mizuno, Terumi, Tsuyama, Naohiro, Hayashi, Yuzo, Dohi, Kiyohiko, Nakamura, Nori, Akiyama, Mitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919182/
https://www.ncbi.nlm.nih.gov/pubmed/8100564
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00171.x