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The Rat Urinary Bladder as a New Target of Heterocyclic Amine Carcinogenicity: Tumor Induction by 3‐Amino‐l‐methyl‐5H‐pyrido[4,3‐β]indole Acetate

In order to examine the carcinogenicity of 3‐amino‐l‐methyl‐5H‐pyrido[4,3‐β]indole acetate (Trp‐P‐2), 30 male and 30 female F344 rats were maintained on diet containing 0, 30, or 100 ppm Trp‐P‐2 for 112 weeks. The overall mean chemical intakes in the 100 ppm and 30 ppm groups were 3.84 and 1.14 mg/k...

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Detalles Bibliográficos
Autores principales: Takahashi, Michihito, Toyoda, Kazuhiro, Aze, Yoshiya, Furuta, Kyoko, Mitsumori, Kunitoshi, Hayashi, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919261/
https://www.ncbi.nlm.nih.gov/pubmed/8407549
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02057.x