High Sensitivity of LEC Rats with Chronic Hepatitis to Hepatocarcinogenesis: Decreases in Unscheduled and Replicative DNA Synthesis of the Hepatocytes

We carried out the following three experiments to clarify the mechanism of hepatocarcinogenesis in Long‐Evans Cinnamon (LEC) rats. (1) Sensitivity to diethylnitrosamine (DEN): LEC rats (8 and 25 weeks old) without and with hepatitis and age‐matched F344 rats were administered an intraperitoneal inje...

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Detalles Bibliográficos
Autores principales: Sakamoto, Hirofumi, Sawada, Norimasa, Kamimura, Yasuhiro, Enomoto, Katsuhiko, Mori, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919285/
https://www.ncbi.nlm.nih.gov/pubmed/8407564
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00186.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919285/
https://www.ncbi.nlm.nih.gov/pubmed/8407564
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00186.x

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