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Inhibition of Cisplatin‐mediated DNA Damage in vitro by Ribonucleotides

Effects of ribonucleotides on cis‐diamminedichloroplatinum(II) (cisplatin)‐mediated DNA damage were studied by incubating pUC18 DNA with cisplatin in the presence of nucleotide, and by monitoring conformational change and sensitivity change to restriction enzyme HpaII of the DNA due to the platinum‐...

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Detalles Bibliográficos
Autores principales: Seki, Shuji, Hongo, Atsushi, Zhang, Bo, Akiyama, Kosuke, Sarker, Altaf H., Kudo, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919301/
https://www.ncbi.nlm.nih.gov/pubmed/8390426
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00159.x