Clonal Analysis of Multiple Point Mutations in the N‐ras Gene in Patients with Acute Myeloid Leukemia

We have screened mutations of the N‐ras gene at codons 12, 13, and 61 in leukemia cells obtained from 100 patients with acute myeloid leukemia (AMD, and found mutated N‐ras alleles in 9 patients. We further analyzed the polyclonality of multiple N‐ras gene mutations in 4 AML patients. One patient, w...

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Detalles Bibliográficos
Autores principales: Kubo, Kazuaki, Naoe, Tomoki, Kiyoi, Hitoshi, Fukutani, Hisashi, Kato, Yoshiro, Oguri, Takashi, Yamamori, Shunji, Akatsuka, Yoshiki, Kodera, Yoshihisa, Ohno, Ryuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919305/
https://www.ncbi.nlm.nih.gov/pubmed/8514604
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00147.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919305/
https://www.ncbi.nlm.nih.gov/pubmed/8514604
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00147.x

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