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Establishment of a Human Small Cell Lung Carcinoma Cell Line Carrying Amplification of c‐myc Gene and Chromosomal Translocation of t(3p;6p) and t(12q;17p)

A transplantable tumor and an in vitro culture cell line (GK‐T3) were established from metastatic liver tissue of human small cell lung carcinoma (SCLC). Southern blot analysis revealed about 30‐fold amplification of c‐myc gene in the tumor cells in liver, xenografts, and in vitro cell line. The deg...

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Detalles Bibliográficos
Autores principales: Kato, Atsushi, Kamiyama, Takashi, Yamaguchi, Sachiko, Sudo, Katsuko, Mori, Shigeo, Sekiguchi, Morimasa, Aoki, Nobuo, Shibuya, Masabumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919310/
https://www.ncbi.nlm.nih.gov/pubmed/8390424
http://dx.doi.org/10.1111/j.1349-7006.1993.tb00143.x