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Potentiation of in vivo Antitumor Effects of Recombinant Interleukin‐1α by Gelatin Conjugation

Chemical conjugation of a recombinant human interleukin‐1α (IL‐1) with gelatin was conducted using a water‐soluble carbodiimide in an attempt to augment the indirect effect of IL‐1 on in vivo tumor cell growth in mice. Chromatographic studies of the IL‐1‐gelatin conjugate demonstrated that the appar...

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Detalles Bibliográficos
Autores principales: Tabata, Yasuhiko, Uno, Kazuko, Ikada, Yoshito, Kishida, Tsunataro, Muramatsu, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919326/
https://www.ncbi.nlm.nih.gov/pubmed/8340257
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02029.x