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Mitotic Activation of c‐Src Is Suppressed by Csk

The kinase activity of the proto‐oncogene product, c‐Src, increases during mitosis through partial dephosphorylation of Tyr527, the negative regulatory site of c‐Src. To examine whether or not Csk, a candidate kinasc specific for Tyr527, is involved in this regulation, we developed a BalbJc 3T3 cell...

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Detalles Bibliográficos
Autores principales: Ohsato, Yoshiharu, Nada, Shigeyuki, Okada, Masato, Nakagawa, Hachiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919353/
https://www.ncbi.nlm.nih.gov/pubmed/7525522
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02900.x