Differential Effect of Duocarmycin A and Its Novel Derivative DU‐86 on DNA Strand Breaks in HeLa S(3) Cells

Duocarmycin A (DUMA) and DU‐86, a semisynthetic derivative of duocarmycins (DUMs) and a possible active form of KW‐2189, both showed potent cell growth‐inhibitory and cell‐killing activities against human uterine cervix carcinoma HeLa (83) cells. Both drugs showed similar profiles of inhibition of m...

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Detalles Bibliográficos
Autores principales: Okamoto, Akihiko, Asai, Akira, Saito, Hiromitsu, Okabe, Masami, Gomi, Katsushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919396/
https://www.ncbi.nlm.nih.gov/pubmed/7852193
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02944.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919396/
https://www.ncbi.nlm.nih.gov/pubmed/7852193
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02944.x

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