Activation of 2‐Hydroxyamino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridne by cDNA‐expressed Human and Rat Arylsulfotransferases

Sulfation plays an obligatory role in the activation of N‐hydroxy derivatives of carcinogenic aryl‐amiric(amide)s and heterocyclic amines. We found that the hepatic sulfotransferase‐mediated covalent binding of (3)H‐labeled 2‐hydroxyamino‐1‐inethy1‐6‐phenylimidazo[4,5‐b]pyridine (N‐OH‐PhIP) to calf...

Descripción completa

Detalles Bibliográficos
Autores principales: Ozawa, Shogo, Chou, Hsien‐Chang, Kadlubar, Fred F., Nagata, Kiyoshi, Yaraazoe, Yasushi, Kato, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919400/
https://www.ncbi.nlm.nih.gov/pubmed/7852185
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02933.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919400/
https://www.ncbi.nlm.nih.gov/pubmed/7852185
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02933.x

Ejemplares similares