Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane

TORC1 is a central regulator of cell growth in response to amino acids. The role of the evolutionarily conserved Gtr/Rag pathway in the regulation of TORC1 is well-established. Recent genetic studies suggest that an additional regulatory pathway, depending on the activity of Pib2, plays a role in TO...

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Detalles Bibliográficos
Autores principales: Ukai, Hirofumi, Araki, Yasuhiro, Kira, Shintaro, Oikawa, Yu, May, Alexander I., Noda, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919408/
https://www.ncbi.nlm.nih.gov/pubmed/29698392
http://dx.doi.org/10.1371/journal.pgen.1007334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919408/
https://www.ncbi.nlm.nih.gov/pubmed/29698392
http://dx.doi.org/10.1371/journal.pgen.1007334

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