Different Modes of Cell‐killing Action between DNA Topoisomerase I and II Inhibitors Revealed by Kinetic Analysis

We compared the modes of cell‐killing by DNA topoisomerase I and II inhibitors. The effects of camptothecin (CPT), KT‐6528 and UCE6 upon colony formation by inhibiting DNA topoisomerase I, and of etoposide (VF‐16), teniposide, amsacrine and UCT4‐A as inhibitors of DNA topoisomerase II were analyzed...

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Detalles Bibliográficos
Autores principales: Inaba, Makoto, Mitsuhashi, Junko, Kawada, Shouzou, Nakano, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919418/
https://www.ncbi.nlm.nih.gov/pubmed/8144400
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02081.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919418/
https://www.ncbi.nlm.nih.gov/pubmed/8144400
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02081.x

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