In vivo Efficacy of Neocarzinostatin Coupled with Fab Human/Mouse Chimeric Monoclonal Antibody A7 against Human Colorectal Cancer

The anticancer polypeptide neocarzinostatin (NCS) was covalently coupled to a human/mouse chimeric Fab A7 monoclonal antibody (chFabA7) and the in vivo efficacy of this conjugate was examined. NCS concentration assay was carried out, and acute toxicity and tumoricidal effects were examined. The conc...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Toshiharu, Tsurumi, Hiroshi, Kotani, Tatsuya, Yamaoka, Nobuki, Otsuji, Eigo, Kitamura, Kazuya, Takahashi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919422/
https://www.ncbi.nlm.nih.gov/pubmed/8144398
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02078.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919422/
https://www.ncbi.nlm.nih.gov/pubmed/8144398
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02078.x

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