Cyclosporin A Enhances Susceptibility of Multi‐drug Resistant Human Cancer Cells to Anti‐P‐glycoprotein Antibody‐dependent Cytotoxicity of Monocytes, but Not of Lymphocytes

Cyclosporin A (CsA) was previously found to bind to P‐glycoprotein expressed on multidrug‐resistant (MDR) cancer cells. In the present study, the effect of CsA on anti‐P‐glycoprotein monoclonal antibody (mAb)‐dependent cell‐mediated cytotoxicity (ADCC) against human MDR cells was examined. The ADCC...

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Detalles Bibliográficos
Autores principales: Yano, Seiji, Sone, Saburo, Nishioka, Yasuhiko, Naito, Mikihiko, Tsuruo, Takashi, Ogura, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919430/
https://www.ncbi.nlm.nih.gov/pubmed/7511575
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02082.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919430/
https://www.ncbi.nlm.nih.gov/pubmed/7511575
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02082.x

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