BE‐23372M, a Novel and Specific Inhibitor for Epidermal Growth Factor Receptor Kinase

The fungal metabolite BE‐23372M is a structurally novel protein kinase inhibitor. Its IC(50) for epidermal growth factor (EGF) receptor kinase was 0.03 μM. IC(50) values of BE‐23372M for other protein tyrosine kinases, erbB‐2, p43(v‐abl), insulin receptor kinase, and p60(c‐src) were 0.42, 1.0, 3.3,...

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Detalles Bibliográficos
Autores principales: Tanaka, Seiichi, Okabe, Takayoshi, Chieda, Shinya, Endo, Kaori, Kanoh, Tomoko, Okura, Akira, Yoshida, Eisaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919452/
https://www.ncbi.nlm.nih.gov/pubmed/8188523
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02090.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919452/
https://www.ncbi.nlm.nih.gov/pubmed/8188523
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02090.x

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