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Active Efflux System for Cisplatin in Cisplatin‐resistant Human KB Cells

Mutants, KCP‐4 and PC‐5, resistant to an anticancer agent, cisplatin, were selected in multiple steps from human epidermoid KB carcinoma cells and human prostate PC‐3 carcinoma cells, respectively. KCP‐4 and PC‐5 were 63 and 10 fold more resistant to cisplatin than the parental cells, respectively....

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Detalles Bibliográficos
Autores principales: Fujii, Ryu‐ichi, Mutoh, Masato, Niwa, Kiyoshi, Yamada, Kazutaka, Aikou, Takashi, Nakagawa, Masayuki, Kuwano, Michihiko, Akiyama, Shin‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919474/
https://www.ncbi.nlm.nih.gov/pubmed/8200854
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02376.x