Improvement of Therapeutic Effect by Using Fab' Fragment in the Treatment of Carcinoembryonic Antigen‐positive Human Solid Tumors with Adriamycinentrapped Immunoliposomes

To improve the therapeutic efficiency adriamycin entrapped in antibody‐conjugated liposomes, Fab' fragment was used instead of the whole antibody molecule. The murine monoclonal antibody, 21B2, against human carcinoembryonic antigen (CEA) was digested with pepsin, and the thiol residue of intra...

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Detalles Bibliográficos
Autores principales: Uyama, Ichiro, Kumai, Koichiro, Yasuda, Tatsuji, Tagawa, Toshiaki, Ishibiki, Kyuya, Kitajima, Masaki, Tadakuma, Takushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919477/
https://www.ncbi.nlm.nih.gov/pubmed/8200855
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02377.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919477/
https://www.ncbi.nlm.nih.gov/pubmed/8200855
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02377.x

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