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The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors

The neurons that form the mammalian neocortex originate from progenitor cells in the ventricular (VZ) and subventricular zone (SVZ). Newborn neurons are multipolar but become bipolar during their migration from the germinal layers to the cortical plate (CP) by forming a leading process and an axon t...

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Detalles Bibliográficos
Autores principales: Dhumale, Pratibha, Menon, Sindhu, Chiang, Joanna, Püschel, Andreas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919486/
https://www.ncbi.nlm.nih.gov/pubmed/29698519
http://dx.doi.org/10.1371/journal.pone.0196698