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Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase

Upon their translocation into the mitochondrial matrix, the N-terminal pre-sequence of nuclear-encoded proteins undergoes cleavage by mitochondrial processing peptidases. Some proteins require more than a single processing step, which involves several peptidases. Down-regulation of the putative Tryp...

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Detalles Bibliográficos
Autores principales: Peña-Diaz, Priscila, Mach, Jan, Kriegová, Eva, Poliak, Pavel, Tachezy, Jan, Lukeš, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919513/
https://www.ncbi.nlm.nih.gov/pubmed/29698456
http://dx.doi.org/10.1371/journal.pone.0196474