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Brief exposure to obesogenic diet disrupts brain dopamine networks

OBJECTIVE: We have previously demonstrated that insulin signaling, through the downstream signaling kinase Akt, is a potent modulator of dopamine transporter (DAT) activity, which fine-tunes dopamine (DA) signaling at the synapse. This suggests a mechanism by which impaired neuronal insulin receptor...

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Detalles Bibliográficos
Autores principales: Barry, Robert L., Byun, Nellie E., Williams, Jason M., Siuta, Michael A., Tantawy, Mohammed N., Speed, Nicole K., Saunders, Christine, Galli, Aurelio, Niswender, Kevin D., Avison, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919534/
https://www.ncbi.nlm.nih.gov/pubmed/29698491
http://dx.doi.org/10.1371/journal.pone.0191299