Cargando…

Aberrant CYP1A1 Induction: Discrepancy of CYP1A1 mRNA and Aryl Hydrocarbon Hydroxylase Activity in Mutant Cells of Mouse Hepatoma Line, Hepa‐1

We have isolated new benzo[α]pyrene‐resistant clones, cl‐21 and cl‐32, of the mouse hepatoma line, Hepa‐1. CYP1A1‐dependent aryl hydrocarbon hydroxylase activity is not inducible by 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin or 3‐methylcholanthrene in these two cell lines. However, mRNA of CYP1A1 is induci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kikuchi, Hideaki, Usuda, Masahiro, Sagami, Ikuko, Ikawa, Shuntaro, Watanabe, Minro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1994
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919553/ https://www.ncbi.nlm.nih.gov/pubmed/8071113 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02419.x

Ejemplares similares

The Relationship between Aryl Hydrocarbon Hydroxylase and Polymorphisms of the CYP1A1 Gene
por: Kiyohara, Chikako, et al.
Publicado: (1996)

Camel Milk Modulates the Expression of Aryl Hydrocarbon Receptor-Regulated Genes, Cyp1a1, Nqo1, and Gsta1, in Murine hepatoma Hepa 1c1c7 Cells
por: Korashy, Hesham M., et al.
Publicado: (2012)

The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor
por: Ciolino, H P, et al.
Publicado: (1999)

The aryl hydrocarbon receptor and retinoid receptors cross-talk at the CYP1A1 promoter in vitro
por: Hessel-Pras, Stefanie, et al.
Publicado: (2018)

Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells
por: Li, Hongfang, et al.
Publicado: (2020)

Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes
por: Rasmussen, Martin Krøyer, et al.
Publicado: (2016)

Association between Restriction Fragment Length Polymorphism of the Human Cytochrome P450IIE1 Gene and Susceptibility to Lung Cancer
por: Uematsu, Fumiyuki, et al.
Publicado: (1991)

E-cigarette Aerosol Condensate Enhances Metabolism of Benzo(a)pyrene to Genotoxic Products, and Induces CYP1A1 and CYP1B1, Likely by Activation of the Aryl Hydrocarbon Receptor
por: Sun, Yuan-Wan, et al.
Publicado: (2019)

The Effect of Aromatic Hydrocarbon Receptor on the Phenotype of the Hepa 1c1c7 Murine Hepatoma Cells in the Absence of Dioxin
por: Wang, Feng, et al.
Publicado: (2007)

Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation
por: Alessandrini, Francesca, et al.
Publicado: (2022)

Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels
por: Jacob, Aude, et al.
Publicado: (2011)

INDUCTION OF ARYL HYDROCARBON (BENZO[a]PYRENE) HYDROXYLASE AND TYROSINE AMINOTRANSFERASE IN HEPATOMA CELLS IN CULTURE
por: Whitlock, James P., et al.
Publicado: (1974)

Endosulfan Induces CYP1A1 Expression Mediated through Aryl Hydrocarbon Receptor Signal Transduction by Protein Kinase C
por: Han, Eun Hee, et al.
Publicado: (2015)

Identification and Analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in Cynomolgus Macaques
por: UNO, Yasuhiro, et al.
Publicado: (2014)

Stability of the Aryl hydrocarbon Receptor and its Regulated Genes in the Low activity Variant of Hepa-1 cell line
por: Humphrey-Johnson, Andria, et al.
Publicado: (2015)

Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1
por: Takeda, Yoshimichi, et al.
Publicado: (2023)

Detection of Small CYP11B1 Deletions and One Founder Chimeric CYP11B2/CYP11B1 Gene in 11β-Hydroxylase Deficiency
por: Xie, Hua, et al.
Publicado: (2022)

Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells
por: Vyhlídalová, Barbora, et al.
Publicado: (2020)

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
por: Kapelyukh, Y., et al.
Publicado: (2019)

Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk
por: Bethke, Lara, et al.
Publicado: (2007)

Streptococcus gallolyticus Increases Expression and Activity of Aryl Hydrocarbon Receptor-Dependent CYP1 Biotransformation Capacity in Colorectal Epithelial Cells
por: Taddese, Rahwa, et al.
Publicado: (2021)

25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification
por: Yimamu, Yilimulati, et al.
Publicado: (2022)

Epigenetic Determinants of CYP1A1 Induction by the Aryl Hydrocarbon Receptor Agonist 3,3',4,4',5-Pentachlorobiphenyl (PCB 126)
por: Vorrink, Sabine U., et al.
Publicado: (2014)

Transgenic Overexpression of Aryl Hydrocarbon Receptor Repressor (AhRR) and AhR-Mediated Induction of CYP1A1, Cytokines, and Acute Toxicity
por: Vogel, Christoph F.A., et al.
Publicado: (2016)

β-naphthoflavone-induced upregulation of CYP1B1 expression is mediated by the preferential binding of aryl hydrocarbon receptor to unmethylated xenobiotic responsive elements
por: Miura, Toshitaka, et al.
Publicado: (2021)

Reversal of obesity and liver steatosis in mice via inhibition of aryl hydrocarbon receptor and altered gene expression of CYP1B1, PPARα, SCD1, and osteopontin
por: Rojas, Itzel Y., et al.
Publicado: (2020)

A CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1
por: Sundberg, Christopher D, et al.
Publicado: (2019)

Profiling of CYP4Z1 and CYP1B1 expression in bladder cancers
por: Al-saraireh, Yousef M., et al.
Publicado: (2021)

Hydration and Structural Adaptations of the Human CYP1A1, CYP1A2, and CYP1B1 Active Sites by Molecular Dynamics Simulations
por: Dutkiewicz, Zbigniew, et al.
Publicado: (2023)

Polycyclic aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment length polymorphism.
por: Shields, P G, et al.
Publicado: (1992)

Expression Profile of CYP1A1 and CYP1B1 Enzymes in Colon and Bladder Tumors
por: Androutsopoulos, Vasilis P., et al.
Publicado: (2013)

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
por: Fernandes, Glaucia Maria M, et al.
Publicado: (2016)

Hydrostatic pressure regulates CYP1A2 expression in human hepatocytes via a mechanosensitive aryl hydrocarbon receptor-dependent pathway
por: Burton, Lewis, et al.
Publicado: (2020)

Differential Susceptibility to Benzo[a]pyrene Exposure during Gestation and Lactation in Mice with Genetic Variations in the Aryl Hydrocarbon Receptor and Cyp1 Genes
por: Feltner, Mackenzie, et al.
Publicado: (2023)

Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 during development
por: Da Costa, N. Meireles, et al.
Publicado: (2016)

Alizarin, an Agonist of AHR Receptor, Enhances CYP1A1 Enzyme Activity and Induces Transcriptional Changes in Hepatoma Cells
por: Liang, Shengxian, et al.
Publicado: (2023)

Enzymatic Characterization and Comparison of Two Steroid Hydroxylases CYP154C3-1 and CYP154C3-2 from Streptomyces Species
por: Subedi, Pradeep, et al.
Publicado: (2021)

The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
por: Arici, Merve, et al.
Publicado: (2017)

Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells
por: Xu, Shuoqi, et al.
Publicado: (2014)

Genetic polymorphisms in CYP1A1, CYP1B1 and COMT genes in Greenlandic Inuit and Europeans
por: Ghisari, Mandana, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_2lj480fdnvrltf1l49kj8qaeb4