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N‐Nitroso‐2‐acetylaminofluorene: A Direct‐acting Carcinogen Inducing Hepatocellular Carcinoma in Sprague‐Dawley Rats

To compare the hepatotoxicity and hepatocarcinogenicity of N‐nitroso‐2‐acetylaminofluorene (NO‐AAF) and its parent compound, 2‐acetylaminofluorene (AAF), male Sprague‐Dawley rats were given intraperitoneal (i.p.) or subcutaneous (s.c.) injections of AAF or NO‐AAF (60 mg/kg body weight/week) for ten...

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Detalles Bibliográficos
Autores principales: Ho, Yuan‐Soon, Lin, Jen‐Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919556/
https://www.ncbi.nlm.nih.gov/pubmed/7928624
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02950.x