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High‐yield Induction of Uterine Endometrial Adenocarcinomas in Donryu Rats by a Single Intra‐uterine Administration of N‐Ethyl‐N‐nitro‐N‐nitrosoguanidine via the Vagina

A total of 130 female Donryu rats (10‐week‐old) were divided into two groups; 80 animals in the experimental group were given a single intra‐uterine administration of 20 mg/kg N‐ethyl‐N‐nitro‐N‐nitrosoguanidine (ENNG) dissolved in polyethylene glycol (PEG) via the vagina without laparotomy, and 50 a...

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Detalles Bibliográficos
Autores principales: Ando‐Lu, Jin, Takahashi, Masakazu, Imai, Shigeru, Ishihara, Roza, Kitamura, Tsuyoshi, Iijima, Tetsuo, Takano, Satoshi, Nishiyama, Kan, Suzuki, Kenji, Maekawa, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919559/
https://www.ncbi.nlm.nih.gov/pubmed/7928623
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02949.x