Celecoxib use and circulating oxylipins in a colon polyp prevention trial

Drugs that inhibit cyclooxygenase (COX)-2 and the metabolism of arachidonic acid (ARA) to prostaglandin E(2) are potent anti-inflammatory agents used widely in the treatment of joint and muscle pain. Despite their benefits, daily use of these drugs has been associated with hypertension, cardiovascul...

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Detalles Bibliográficos
Autores principales: Martinez, Jessica A., Yang, Jun, Wertheim, Betsy C., Roe, Denise J., Schriewer, Alexander, Lance, Peter, Alberts, David S., Hammock, Bruce D., Thompson, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919576/
https://www.ncbi.nlm.nih.gov/pubmed/29698447
http://dx.doi.org/10.1371/journal.pone.0196398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919576/
https://www.ncbi.nlm.nih.gov/pubmed/29698447
http://dx.doi.org/10.1371/journal.pone.0196398

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