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Celecoxib use and circulating oxylipins in a colon polyp prevention trial
Drugs that inhibit cyclooxygenase (COX)-2 and the metabolism of arachidonic acid (ARA) to prostaglandin E(2) are potent anti-inflammatory agents used widely in the treatment of joint and muscle pain. Despite their benefits, daily use of these drugs has been associated with hypertension, cardiovascul...
Autores principales: | Martinez, Jessica A., Yang, Jun, Wertheim, Betsy C., Roe, Denise J., Schriewer, Alexander, Lance, Peter, Alberts, David S., Hammock, Bruce D., Thompson, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919576/ https://www.ncbi.nlm.nih.gov/pubmed/29698447 http://dx.doi.org/10.1371/journal.pone.0196398 |
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