Cargando…
MicroRNA-425 and microRNA-155 cooperatively regulate atrial natriuretic peptide expression and cGMP production
AIMS: Atrial natriuretic peptide (ANP), secreted primarily by atrial cardiomyocytes, decreases blood pressure by raising cyclic 3’,5’-guanosine monophosphate (cGMP) levels and inducing vasorelaxation, natriuresis, and diuresis. Raising the level of ANP has been shown to be an effective treatment for...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919659/ https://www.ncbi.nlm.nih.gov/pubmed/29698509 http://dx.doi.org/10.1371/journal.pone.0196697 |