MicroRNA-425 and microRNA-155 cooperatively regulate atrial natriuretic peptide expression and cGMP production

AIMS: Atrial natriuretic peptide (ANP), secreted primarily by atrial cardiomyocytes, decreases blood pressure by raising cyclic 3’,5’-guanosine monophosphate (cGMP) levels and inducing vasorelaxation, natriuresis, and diuresis. Raising the level of ANP has been shown to be an effective treatment for...

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Detalles Bibliográficos
Autores principales: Vandenwijngaert, Sara, Ledsky, Clara D., Agha, Obiajulu, Wu, Connie, Hu, Dongjian, Bagchi, Aranya, Domian, Ibrahim J., Buys, Emmanuel S., Newton-Cheh, Christopher, Bloch, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919659/
https://www.ncbi.nlm.nih.gov/pubmed/29698509
http://dx.doi.org/10.1371/journal.pone.0196697

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