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A computational study of astrocytic glutamate influence on post-synaptic neuronal excitability

The ability of astrocytes to rapidly clear synaptic glutamate and purposefully release the excitatory transmitter is critical in the functioning of synapses and neuronal circuits. Dysfunctions of these homeostatic functions have been implicated in the pathology of brain disorders such as mesial temp...

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Detalles Bibliográficos
Autores principales: Flanagan, Bronac, McDaid, Liam, Wade, John, Wong-Lin, KongFatt, Harkin, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919689/
https://www.ncbi.nlm.nih.gov/pubmed/29659572
http://dx.doi.org/10.1371/journal.pcbi.1006040