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Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly
In this work, we assess a previously advanced hypothesis that predicts the existence of ion channels in the capsid of small and non-enveloped icosahedral viruses. With this purpose we examine Triatoma Virus (TrV) as a case study. This virus has a stable capsid under highly acidic conditions but disa...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919690/ https://www.ncbi.nlm.nih.gov/pubmed/29659564 http://dx.doi.org/10.1371/journal.pcbi.1006082 |