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Multiscale modelization in a small virus: Mechanism of proton channeling and its role in triggering capsid disassembly

In this work, we assess a previously advanced hypothesis that predicts the existence of ion channels in the capsid of small and non-enveloped icosahedral viruses. With this purpose we examine Triatoma Virus (TrV) as a case study. This virus has a stable capsid under highly acidic conditions but disa...

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Detalles Bibliográficos
Autores principales: Viso, Juan Francisco, Belelli, Patricia, Machado, Matías, González, Humberto, Pantano, Sergio, Amundarain, María Julia, Zamarreño, Fernando, Branda, Maria Marta, Guérin, Diego M. A., Costabel, Marcelo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919690/
https://www.ncbi.nlm.nih.gov/pubmed/29659564
http://dx.doi.org/10.1371/journal.pcbi.1006082