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Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content

A constellation of metabolic disorders, including obesity, dysregulated lipids, and elevations in blood glucose levels, has been associated with cardiovascular disease and diabetes. Analysis of data from recently published genome-wide association studies (GWAS) demonstrated that reduced-function pol...

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Detalles Bibliográficos
Autores principales: Liang, Xiaomin, Yee, Sook Wah, Chien, Huan-Chieh, Chen, Eugene C., Luo, Qi, Zou, Ling, Piao, Meiling, Mifune, Arias, Chen, Ligong, Calvert, Meredith E., King, Sarah, Norheim, Frode, Abad, Janna, Krauss, Ronald M., Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919692/
https://www.ncbi.nlm.nih.gov/pubmed/29659562
http://dx.doi.org/10.1371/journal.pbio.2002907