An interplay between multiple sirtuins promotes completion of DNA replication in cells with short telomeres

The evolutionarily-conserved sirtuin family of histone deacetylases regulates a multitude of DNA-associated processes. A recent genome-wide screen conducted in the yeast Saccharomyces cerevisiae identified Yku70/80, which regulate nonhomologous end-joining (NHEJ) and telomere structure, as being ess...

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Detalles Bibliográficos
Autores principales: Simoneau, Antoine, Ricard, Étienne, Wurtele, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919697/
https://www.ncbi.nlm.nih.gov/pubmed/29659581
http://dx.doi.org/10.1371/journal.pgen.1007356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919697/
https://www.ncbi.nlm.nih.gov/pubmed/29659581
http://dx.doi.org/10.1371/journal.pgen.1007356

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