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Dosage-Dependent Expression Variation Suppressed on the Drosophila Male X Chromosome

DNA copy number variation is associated with many high phenotypic heterogeneity disorders. We systematically examined the impact of Drosophila melanogaster deletions on gene expression profiles to ask whether increased expression variability owing to reduced gene dose might underlie this phenotypic...

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Detalles Bibliográficos
Autores principales: Lee, Hangnoh, Cho, Dong-Yeon, Wojtowicz, Damian, Harbison, Susan T., Russell, Steven, Oliver, Brian, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919722/
https://www.ncbi.nlm.nih.gov/pubmed/29242386
http://dx.doi.org/10.1534/g3.117.300400