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Highly Efficient Site-Specific Mutagenesis in Malaria Mosquitoes Using CRISPR

Anopheles mosquitoes transmit at least 200 million annual malaria infections worldwide. Despite considerable genomic resources, mechanistic understanding of biological processes in Anopheles has been hampered by a lack of tools for reverse genetics. Here, we report successful application of the CRIS...

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Detalles Bibliográficos
Autores principales: Li, Ming, Akbari, Omar S., White, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919725/
https://www.ncbi.nlm.nih.gov/pubmed/29233915
http://dx.doi.org/10.1534/g3.117.1134