Direct Testing for Allele-Specific Expression Differences Between Conditions

Allelic imbalance (AI) indicates the presence of functional variation in cis regulatory regions. Detecting cis regulatory differences using AI is widespread, yet there is no formal statistical methodology that tests whether AI differs between conditions. Here, we present a novel model and formally t...

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Detalles Bibliográficos
Autores principales: León-Novelo, Luis, Gerken, Alison R., Graze, Rita M., McIntyre, Lauren M., Marroni, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919738/
https://www.ncbi.nlm.nih.gov/pubmed/29167272
http://dx.doi.org/10.1534/g3.117.300139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919738/
https://www.ncbi.nlm.nih.gov/pubmed/29167272
http://dx.doi.org/10.1534/g3.117.300139

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