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Direct Testing for Allele-Specific Expression Differences Between Conditions
Allelic imbalance (AI) indicates the presence of functional variation in cis regulatory regions. Detecting cis regulatory differences using AI is widespread, yet there is no formal statistical methodology that tests whether AI differs between conditions. Here, we present a novel model and formally t...
Autores principales: | León-Novelo, Luis, Gerken, Alison R., Graze, Rita M., McIntyre, Lauren M., Marroni, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919738/ https://www.ncbi.nlm.nih.gov/pubmed/29167272 http://dx.doi.org/10.1534/g3.117.300139 |
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