Transcriptional Profiling of Saccharomyces cerevisiae Reveals the Impact of Variation of a Single Transcription Factor on Differential Gene Expression in 4NQO, Fermentable, and Nonfermentable Carbon Sources

Cellular metabolism can change the potency of a chemical’s tumorigenicity. 4-nitroquinoline-1-oxide (4NQO) is a tumorigenic drug widely used on animal models for cancer research. Polymorphisms of the transcription factor Yrr1 confer different levels of resistance to 4NQO in Saccharomyces cerevisiae....

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Detalles Bibliográficos
Autores principales: Rong-Mullins, Xiaoqing, Ayers, Michael C., Summers, Mahmoud, Gallagher, Jennifer E. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919752/
https://www.ncbi.nlm.nih.gov/pubmed/29208650
http://dx.doi.org/10.1534/g3.117.300138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919752/
https://www.ncbi.nlm.nih.gov/pubmed/29208650
http://dx.doi.org/10.1534/g3.117.300138

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