Use of a Sibling Subtraction Method for Identifying Causal Mutations in Caenorhabditis elegans by Whole-Genome Sequencing

Whole-genome sequencing (WGS) is an indispensable tool for identifying causal mutations obtained from genetic screens. To reduce the number of causal mutation candidates typically uncovered by WGS, Caenorhabditis elegans researchers have developed several strategies. One involves crossing N2-backgro...

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Detalles Bibliográficos
Autores principales: Joseph, Braveen B., Blouin, Nicolas A., Fay, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919755/
https://www.ncbi.nlm.nih.gov/pubmed/29237702
http://dx.doi.org/10.1534/g3.117.300135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919755/
https://www.ncbi.nlm.nih.gov/pubmed/29237702
http://dx.doi.org/10.1534/g3.117.300135

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