Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

Wnt5a has been implicated in melanoma progression and metastasis, although the exact downstream signaling events that contribute to melanoma metastasis are poorly understood. Wnt5a signaling results in acyl protein thioesterase 1 (APT1) mediated depalmitoylation of pro-metastatic cell adhesion molec...

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Detalles Bibliográficos
Autores principales: Sadeghi, Rochelle Shirin, Kulej, Katarzyna, Kathayat, Rahul Singh, Garcia, Benjamin A, Dickinson, Bryan C, Brady, Donita C, Witze, Eric S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919757/
https://www.ncbi.nlm.nih.gov/pubmed/29648538
http://dx.doi.org/10.7554/eLife.34362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919757/
https://www.ncbi.nlm.nih.gov/pubmed/29648538
http://dx.doi.org/10.7554/eLife.34362

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