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Stochastic tuning of gene expression enables cellular adaptation in the absence of pre-existing regulatory circuitry
Cells adapt to familiar changes in their environment by activating predefined regulatory programs that establish adaptive gene expression states. These hard-wired pathways, however, may be inadequate for adaptation to environments never encountered before. Here, we reveal evidence for an alternative...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919758/ https://www.ncbi.nlm.nih.gov/pubmed/29620524 http://dx.doi.org/10.7554/eLife.31867 |