Cargando…

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength

Diversified neurons are essential for sensorimotor function, but whether astrocytes become specialized to optimize circuit performance remains unclear. Large fast α-motor neurons (FαMNs) of spinal cord innervate fast-twitch muscles that generate peak strength. We report that ventral horn astrocytes...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelley, Kevin W., Ben Haim, Lucile, Schirmer, Lucas, Tyzack, Giulia E., Tolman, Michaela, Miller, John G., Tsai, Hui-Hsin, Chang, Sandra M., Molofsky, Anna V., Yang, Yongjie, Patani, Rickie, Lakatos, Andras, Ullian, Erik M., Rowitch, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919779/
https://www.ncbi.nlm.nih.gov/pubmed/29606582
http://dx.doi.org/10.1016/j.neuron.2018.03.010