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Protein kinase N1 critically regulates cerebellar development and long-term function

Increasing evidence suggests that synapse dysfunctions are a major determinant of several neurodevelopmental and neurodegenerative diseases. Here we identify protein kinase N1 (PKN1) as a novel key player in fine-tuning the balance between axonal outgrowth and presynaptic differentiation in the para...

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Detalles Bibliográficos
Autores principales: zur Nedden, Stephanie, Eith, Rafaela, Schwarzer, Christoph, Zanetti, Lucia, Seitter, Hartwig, Fresser, Friedrich, Koschak, Alexandra, Cameron, Angus J.M., Parker, Peter J., Baier, Gottfried, Baier-Bitterlich, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919825/
https://www.ncbi.nlm.nih.gov/pubmed/29494346
http://dx.doi.org/10.1172/JCI96165